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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIAM1 All Species: 21.52
Human Site: S1036 Identified Species: 78.89
UniProt: Q13009 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13009 NP_003244.2 1591 177508 S1036 L A T M R Q L S D A D K L R K
Chimpanzee Pan troglodytes XP_001162796 1591 177528 S1036 L A T M R Q L S D A D K L R K
Rhesus Macaque Macaca mulatta XP_001098107 1591 177452 S1036 L A T M R Q L S D A D K L R K
Dog Lupus familis XP_544855 1591 177339 T1036 L A T M R Q L T D A D K L R K
Cat Felis silvestris
Mouse Mus musculus Q60610 1591 177515 S1036 L A T T R Q L S D A D K L R K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91620 2061 229913 T1421 L T P S R Q L T D A E K L R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788791 1150 129570 G624 E I I K F Q T G F L K S L E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.4 95.7 N.A. 95.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 27.5 N.A. N.A. 25.4
Protein Similarity: 100 99.8 99.6 97.8 N.A. 97.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 42.9 N.A. N.A. 40.7
P-Site Identity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 66.6 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 80 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 72 0 0 0 0 0 0 0 86 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 86 0 72 0 0 0 15 % D
% Glu: 15 0 0 0 0 0 0 0 0 0 15 0 0 15 0 % E
% Phe: 0 0 0 0 15 0 0 0 15 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 15 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 15 0 0 0 0 0 0 15 86 0 0 86 % K
% Leu: 86 0 0 0 0 0 86 0 0 15 0 0 100 0 0 % L
% Met: 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 86 0 0 0 0 0 0 0 0 86 0 % R
% Ser: 0 0 0 15 0 0 0 58 0 0 0 15 0 0 0 % S
% Thr: 0 15 72 15 0 0 15 29 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _